Edelweiss Connect

AGINKO Research is the premiere CRO for preclinical work in osteoarticular pathologies. We offer a wide range of contract research services to support Drug and Medical Device established companies as well as start-ups and academia. From industry standard protocols to customized research design, our animal models and assays, both on an in vivo or in vitro basis, provide key tools for compound discovery and product development.

Given our expertise, know-how, and network in the field of osteoarticular pathologies, AGINKO today also offers a full range of histology services for your preclinical and clinical trials as well as general consulting services (e.g., regulatory, strategy, financing) devoted to osteoarticular pathologies.


#Osteoarticular #CRO #Cartilage #Repair #Arthritis #Fracture #Osteoporosis #Preclinical #Pain #Disc #Spine #Infection

Across Barriers GmbH provides its customers services and consulting in the fields of in-vitro bioequivalence and pharmaceutical technological development.



Starting with analytical, physicochemical characterization, followed by testing of active com-pound properties on in vitro models for the feasibility, bioavailability, bioequivalence, and also customer oriented consultancy for drug formulation make it possible for Across Barriers to offer a complete service package for each question during the lifetime of the costumer’s product.



Across Barriers is certified in three GLP categories as well as for GMP. Since 2009 Across Barriers is FDA approved. Therefore, every project is performed under the common quality guidance but can also be conducted as a GLP or GMP study which is highly accepted at na-tional and international regulatory authorities.
A team of well-educated and experienced employees and a superbly equipped facility accom-plish the profile of Across Barriers.

FDAS is an experienced, accredited, Independent Contract Services performing chemical and microbiological services for the pharmaceutical industry, globally.
Our strength is the combination of technical experience with cost effective prices & outstanding customer service to fit in to any QMS.

Our experienced analytical team provide all the expertise needed to guarantee timely, accurate results that meet the requirements and rigours of any regulatory body.
The capabilities are listed but not exhaustive:

Raw Material analysis
API & Finished Product testing
Method Development & Validation
Technology Transfer
Stability studies (ICH/VICH)
Microbiological analysis
Technical advice / Consultancy/ Pre-formulation
USP/EP/BP/JP Tests

Customer listing from small companies to Blue Chip Pharmaceutical Global companies. Generic pharmaceutical testing is our speciality. Call us for more information or a confidential discussion.

Within Basel neighbourhood and at the very heart of Europe (the triple border of France, Germany and Switzerland), Firalis is a pioneering biotechnology company, active in discovery, development and qualification of biomarkers (BM).

1) BIOMARKER PRODUCTS
Firalis develops BM-based diagnostic, prognostic and theranostic tools:
● RUO Kits (Research-Use-Only), based on validated innovative biomarkers
● IVD Tools (In Vitro Diagnostic), based on a combination of clinically qualified biomarkers

2) BIOMARKER R&D
● Development of proprietary BMs
- Cardiovascular, Inflammatory, Autoimmune and Neurology
● Drug Safety & Drug Efficacy
● Patient Stratification
● Personalized Medicine

3) BIOMARKER-RELATED CRO SERVICES
BM Discovery for laboratories, biotechs and pharmaceutical industry:
- Proteomics: Soluble biomarker measurements with several immunoassays technologies (ELISA, multiplex and high sensitivity platforms such as Luminex® BioPlex 200™, Meso Scale Discovery®, Singulex Erenna®, Protein Simple Ella™, Olink and Siemens Dimension® EXL™ 200)
- Genomics/Transcriptomics: Targeted sequencing of miRNA and mRNA (HTG EdgeSeq), lncRNA screening via Firalis proprietary platform, Next-Generation Sequencing (NGS) services (RNA-Seq, whole genome and exome sequencing, etc.) and qPCR/microfluidic qPCR (Gene Expression, SNP, CNV, etc.)
- Flow Cytometry: Immunophenotyping of preclinical and clinical samples, monitoring of pharmacodynamics on target cells in response to treatment and biomarker discovery
- Assay development and validation on various platforms, development of critical reagents (antibodies and proteins)
- Biobanking and sample repository services supported by LIMS
- Data analysis using multi-parametric statistics and development of predictive models
- Support of regulatory activities related to biomarker qualification with Health Authorities (FDA/EMA)
- Quality environment (ISO 9001, ISO 13485 (GMP), ISO 17025 (GLP/GCLP))

For more information please visit our website.

Unlike most contract research organizations, Zelmic is entirely focused on one thing and one thing only – getting your drug to where it is most needed, on or through the skin. And we do it faster, more efficiently and with more personal attention than our customers have received elsewhere. So if topical or transdermal drug delivery and avoiding costly delays are your top priorities, our size and unique expertise may be just the advantage you need.
We support and utilize:
• Product development, ranging from pre-formulation and compatibility to formulation development and optimization.
• CMC documentation, in-house and through regulatory partners
• Analytical chemistry services (R&D and GMP), ICH stability studies, method development, forced degradation, and validation services to ensure high-quality methods.
• Performance testing services, (R&D and GMP) IVRT and IVPT
• Topical bioequivalence testing, in-vitro or through clinical partner
• Topical generics

Contact us today for a consultation.