Digital BioPharm ltd.

We are a reliable, self-sustaining computational chemistry company. We offer our software and expertise to both smaller biotech companies and big pharma, either as a CRO or as licensed software, for use in the preclinical stages of drug discovery.

Are you a biotech kicking off a new project, looking for rational computer-aided drug design (CADD) to accelerate your hit discovery? We use our own software tools and a structure-based approach to identify novel small molecules targeting any protein family.

Do you need diverse comp. chem. expertise, but only employ a small in-house team, or no team at all? When you hire us as a CRO, we source our entire team’s experience in areas including structure-based design, chemoinformatics, quantum mechanics, and molecular dynamics.

Do you struggle with third-party software, hidden license requirements, and missing features? We develop our own software for most applications, precluding the need to sign other agreements or to procure other tools. We can also adjust and enhance our procedures to accommodate different project workflows. Our software works on PC, Linux, and Mac and we will run demos and workshops.

Are you looking for a long-term partner with flexibility in how you collaborate? We construct our agreements on FFS or FTE bases and generally do not retain IP on your projects. We conduct feasibility studies before spending time and money on projects that are unlikely to be successful. We will provide reports, communicate regularly, and return any generated data.

James Talton, CEO of Alchem Laboratories says, “We reviewed multiple software packages and MFI ranked in the top 10. Adding in their service and expertise made them an excellent partner on our DOD project. We’re excited by the results thus far and will absolutely continue working with their team in the future.

Contact us to start your project today! Don't forget to follow us on Twitter @MolForecaster!
Find our testimonials and references on our website!

Absorption Systems, a Pharmaron company, is a full-service nonclinical CRO developing innovative services and solutions for the pharmaceutical, biotech, medical device and regenerative medicine industry. Our services include research and testing for small molecules, large molecules, biologics, medical device and cell and gene therapy products. The company's mission is to continually develop innovative research tools that can be used to accurately predict human outcomes or to explain unanticipated outcomes when they occur. The company's facilities are strategically located in Philadelphia, San Diego, and Boston, servicing hundreds of customers throughout the world. Our focus is to maintain accuracy, timelines, and reliability at every stage of development. For more information on the company's comprehensive contract services and applied research programs, please visit absorption.com.

WuXi AppTec provides a broad portfolio of R&D and manufacturing services that enable companies in the pharmaceutical, biotech and medical device industries worldwide to advance discoveries and deliver groundbreaking treatments to patients. As an innovation-driven and customer-focused company, WuXi AppTec helps our partners improve the productivity of advancing healthcare products through cost-effective and efficient solutions. With industry-leading capabilities such as R&D and manufacturing for small molecule drugs, cell and gene therapies, and testing for medical devices, WuXi AppTec’s open-access platform is enabling more than 4,100 collaborators from over 30 countries to improve the health of those in need – and to realize our vision that "every drug can be made and every disease can be treated."

Addex Therapeutics is a clinical-stage pharmaceutical company focused on the development and commercialization of an emerging class of novel orally available small molecule drugs known as allosteric modulators for neurological disorders. Allosteric modulators offer several potential advantages over conventional non-allosteric molecules and may offer an improved therapeutic approach to conventional "orthosteric" small molecule or biological drugs. Addex's allosteric modulator drug discovery platform targets receptors and other proteins that are recognized as essential for therapeutic intervention. Addex's lead drug candidate, dipraglurant (mGlu5 negative allosteric modulator or NAM), is poised to start a pivotal registration clinical trial for Parkinson’s disease levodopa induced dyskinesia (PD-LID) in H1 2021. Addex is also investigating dipraglurant's therapeutic use in blepharospasm (a type of dystonia), for which a clinical trial is expected to be initiated in H1 2021. Addex's third clinical program, ADX71149 (mGlu2 positive allosteric modulator or PAM), developed in collaboration with Janssen Pharmaceuticals, Inc., is scheduled to enter a phase 2a proof of concept clinical study for the treatment of epilepsy in H1 2021. Addex’s GABAB PAM program has been licensed to Indivior PLC for the treatment of addiction. Preclinical programs include GABAB PAM for CMT1A, mGlu7 NAM for PTSD, mGlu2 NAM for mild neurocognitive disorders, mGlu4 PAM for Parkinson’s disease and mGlu3 PAM for neurodegenerative disorders. Addex is listed on the SIX Swiss Exchange and NASDAQ Capital Market, and trades under the ticker symbol "ADXN".

APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Probes, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 20 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.

Qualities
We pay the most careful attention to the quality of our products. All products are manufactured with rigorous guidelines and are accompanied with certificates of analysis, HPLC, Mass Spectrum, and HMNR, as well as in vitro validation. APExBIO products have been cited by many top peer-reviewed journals such as Nature, Cell and Science.

Services
Biologists and Chemists at APExBIO offer extensive tech support to our customers for using the products. You may expect personalized and attentive care from our support staff answering your order and technical inquiries. We also provide custom services including peptide synthesis, custom mRNA synthesis and assay development.