ChromaCon - A YMC Company

Addex Therapeutics is a clinical-stage pharmaceutical company focused on the development and commercialization of an emerging class of novel orally available small molecule drugs known as allosteric modulators for neurological disorders. Allosteric modulators offer several potential advantages over conventional non-allosteric molecules and may offer an improved therapeutic approach to conventional "orthosteric" small molecule or biological drugs. Addex's allosteric modulator drug discovery platform targets receptors and other proteins that are recognized as essential for therapeutic intervention. Addex's lead drug candidate, dipraglurant (mGlu5 negative allosteric modulator or NAM), is poised to start a pivotal registration clinical trial for Parkinson’s disease levodopa induced dyskinesia (PD-LID) in H1 2021. Addex is also investigating dipraglurant's therapeutic use in blepharospasm (a type of dystonia), for which a clinical trial is expected to be initiated in H1 2021. Addex's third clinical program, ADX71149 (mGlu2 positive allosteric modulator or PAM), developed in collaboration with Janssen Pharmaceuticals, Inc., is scheduled to enter a phase 2a proof of concept clinical study for the treatment of epilepsy in H1 2021. Addex’s GABAB PAM program has been licensed to Indivior PLC for the treatment of addiction. Preclinical programs include GABAB PAM for CMT1A, mGlu7 NAM for PTSD, mGlu2 NAM for mild neurocognitive disorders, mGlu4 PAM for Parkinson’s disease and mGlu3 PAM for neurodegenerative disorders. Addex is listed on the SIX Swiss Exchange and NASDAQ Capital Market, and trades under the ticker symbol "ADXN".

Caltag Medsystems (CML) has Four Business Divisions:

1. Distribution of Bioscience and Biomedical reagents and kits to the European markets. Key customer groups are Universities, Hospitals, Pharmaceutical Companies, Biotechnology Companies, Private Laboratories. Caltag Medsystems represents over 50 overseas manufacturers from all quarters of the globe. We are looking for new suppliers who fit with our product portfolio and business strategy.
The Cell Culture section of our portfolio includes human and animal primary cells, stem cells, cell lines and media, skin, healthy & diseased human biological materials, angiogenesis models and transfection reagents. Sample types include blood, plasma, serum, bone marrow, CSF, urine, synovial fluid and many more, and are available as matched samples where needed. We supply reagents for the detection of a wide range of different disease biomarkers, together with primary cells and tissue from 26 different cell systems in the human body. Our human biological materials range is extensive, encompassing a wide range of sample types from normal and diseased individuals.
ELISA Kits, Antibodies, Biochemicals and Small Molecules. We provide over 18,000 ELISA kits across a wide range of disease biomarkers including those for apoptosis, cardiovascular, infection and immunity, cytokine and metabolism research and many more. Antibodies, proteins and controls are also available individually.

2. Cytomark Division (www.cytomark.co.uk) - manufacturer of TransFix for stabilisation of whole blood, cerebrospinal fluid, bone marrow and biopsy samples.

3. Cellworks Division (www.cellworks.co.uk) - manufacturer of primary cell models, primary cells, medium and other primary cell reagents. The Cellworks Division is looking for distributors in countries not already represented on our website.

4. Laboratory Services - CRO laboratory services such as Cell Expansion, Flow Cytometry and Angiogenesis service.

Founded in 2013, Cellin Technologies OÜ pioneered the regenerative medicine arena in Estonia by specializing in analysis, design and production of cell therapy products.

Cellin’s scientific foundation is a set of tools and methods that allow to develop a deep understanding between the stems cells and their biological function and the manufacturing process.

IDT Biologika is a contract development and manufacturing organization with almost 100 years of experience in development and manufacture of live viral vaccines, gene and immune therapeutics, and fill/finish of biologics for the global protection of human health. With the expertise and capacity to handle large-scale campaign production of human vaccines and biopharmaceuticals, IDT Biologika brings development, testing and regulatory excellence along with state-of-the-art manufacturing lines required to advance projects with the highest level of quality, efficiency and consistency of supply.

Recognized for its technically sophisticated contract development, manufacture and handling of biopharmaceuticals in EMA- and FDA-inspected facilities, IDT Biologika has developed into one of the world's leading pharmaceutical and biotechnological companies.
The company's headquarters are located in Dessau-Rosslau , Germany. In the United States, IDT Biologika Corp. is responsible for sales activities throughout North America.

💡 A biotechnology group based on complementary expertise with multidisciplinary know-how

Custom Products & Services delivering a range of integrated biotechnology solutions 🤝

🏢 COMPANIES:

- RD-Biotech SAS (www.rd-biotech.com):
Custom services, Biomanufacturing and purification (monoclonal antibodies, recombinant proteins, plasmids, cells), hybridoma development, expression vectors, transfection, antibody sequencing, chimerization and humanization, analytical services and FastELISA kits for Immunoglobulins quantification and cellular contaminants detection.

- SYnAbs (www.synabs.be):
Primary and Secondary Antibodies Anti-species, Isotype controls, custom services, hybridoma development – rat, guinea pig, murine, Immunoassays

- QVQ (www.qvquality.com)
VHH Phage display services and a large range of VHH products

- Smaltis (www.smaltis.fr)
CRO specialized in microbiology, an high expertise in the fileds of antibiotic resistance, microbiota and strain engineering. Custom services and a large collection of genetically modified bacterial strains.

📈 EFFECTIVE SYNERGY

As part of a team of experts to ensure:
- The development of new biological tools in immunology, molecular biology, cellular engineering
- Identification of new markers
- The development of analytical methods
- Scientific and technical support
- The quality of services and products developed and manufactured in-house

✔ MAIN SECTORS OF ACTIVITY

- Pharmaceutical
- BioTherapeutics
- Biotechnology
- In vitro diagnostics
- Animal health
- Dermo-cosmetic
- Agribusiness
- Life sciences
- Environment
- Research Institutes