ChemBridge Corporation

MedChem Partners is a medicinal chemistry CRO founded in 2006 by Tsvetelina Lazarova and Steven Riesinger. The company is focused on using the extensive experience in early stage company formation and drug discovery to effectively advance small molecule candidates for clients by working closely with the client’s biology and/or chemistry resources. Our experts have extensive experience in moving projects from inception through discovery and into development up to IND enabling toxicology.

At MedChem Partners, we are experts at using synthetic and medicinal chemistry to develop small molecule therapeutics. Unlike large one-stop shops that spread their attention over a variety of tasks, we focus on what we know best. Our expertise is in formulating and implementing a plan to find and optimize small molecules which interact with novel or known biological targets. Whether you already have potential molecules in mind, or have just discovered a novel target, we can develop a plan to find and optimize compounds with therapeutic potential. Since drug discovery is a multidisciplinary endeavor, we have foraged close contacts with a variety of other service providers to augment our expertise in certain areas. Since each company is focused on what it does best, this approach allows us to tap into the best talent in each area. Through out network we have access to in vitro and in vivo testing, in vitro and in vivo pharmacokinetics, computer modeling and in silico prediction, formulation, scale-up and manufacturing, toxicology and regulatory filing, x-ray crystallography, intellectual property and patenting, and consultants in clinical, regulatory, manufacturing, pharmacology, and toxicology.

VENENUM Biodesign is focused on discovering and advancing innovative new medicines for significant unmet medical needs in key therapeutic areas, including; cancer, inflammation, infectious diseases, metabolic diseases, and women’s health. Our most advanced programs are targeting Clostridium difficile infection (CDI) and Type 2 Diabetes (T2D).

Our business model allows us to focus on the creation of high value, innovative small molecule programs against well-validated targets, as well as new targets identified from our own research and to work with partners for clinical and commercial development to bring our products to patients.

Our mission is to improve patients’ lives through the discovery of therapeutic compounds against our novel biological targets. Many of our targets involve novel protein-protein or protein-DNA interactions. Others are more conventional target classes e.g., GPCRs and enzymes. Our goal is to advance our discoveries to medicine through partnership with pharmaceutical companies.

We utilize state-of-the-art assay development and ultra-high throughput screening (UHTS) against our proprietary 6 million ECLiPS compound collection in conjunction with protein engineering and structural biology, medicinal chemistry, and in vivo models.

Absorption Systems, a Pharmaron company, is a full-service nonclinical CRO developing innovative services and solutions for the pharmaceutical, biotech, medical device and regenerative medicine industry. Our services include research and testing for small molecules, large molecules, biologics, medical device and cell and gene therapy products. The company's mission is to continually develop innovative research tools that can be used to accurately predict human outcomes or to explain unanticipated outcomes when they occur. The company's facilities are strategically located in Philadelphia, San Diego, and Boston, servicing hundreds of customers throughout the world. Our focus is to maintain accuracy, timelines, and reliability at every stage of development. For more information on the company's comprehensive contract services and applied research programs, please visit absorption.com.

Atuka provides contract research and consultancy services for the biopharmaceutical industry with world-leading expertise in Parkinson's disease and other neurological conditions. We combine cutting-edge pre-clinical rodent and primate efficacy testing including a comprehensive range of motor and non-motor assays (e.g. cognition and impulse control) with medicinal chemistry services, DMPK and in-vivo imaging in aiding the development of novel therapeutics and diagnostics.

MicroConstants is a GLP-compliant Contract Research Organization focused on performing regulated bioanalysis, drug metabolism, and pharmacokinetic analysis to support discovery, preclinical, and clinical drug development studies. We specialize in method development, validation, and sample analysis of small molecules, macromolecules, biomarkers, and metabolites using LC/MS/MS, HPLC/UV, immunoassay, multiplex, and qPCR techniques.

Since 1998, we have been advancing the drug discovery and development programs of pharmaceutical and biotech companies worldwide. To learn more, please visit http://www.microconstants.com.