Canvax Biotech

BLIRT (Biolab Innovative Research Technologies) is a modern European biotech manufacturer of high quality specialty enzymes and reagents dedicated for application in Life Science.

For over 25 years, BLIRT has been specializing in providing the highest quality products for researchers and scientists. Since 1994, the company began operating in the Polish market as DNA-Gdańsk. From 2007, the company developed and further expanded brand as BLIRT.
A brand new manufacturing facility, commissioned in the late fall of 2017, allows BLIRT to deliver kilogram quantities of any protein expressed in yeast, or bacteria. Every protein in BLIRT’s portfolio is free of any third party IP.

BLIRT also manufactures and sells convenient kits for DNA/RNA isolation and Real-Time PCR. All critical enzymes for the kits are produced internally. Those kits provide excellent yields and added convenience comparing to other products available on the market.

BLIRT’s experience and expertise in development of protein production methods (upstream and downstream), combined with its commercial protein production capacity, makes it an ideal choice for a full service CMO.

BLIRT has three sites in Poland: R&D site, Kits manufacturing facility, and protein production facility.

Clean Cells is a GMP-licensed Contract Development and Manufacturing Organization providing R&D, production and quality control testing services to the biopharmaceutical industry.
Our two-part site located in Western France holds an innovative process development platform, BSL2 and BSL3 GMP manufacturing laboratories and analytical areas to develop bespoke assays and perform GMP testing.
Clean Cells is part of the Clean Biologics group and benefits from the additional experience of sister company Naobios, a CDMO with considerable experience in the development and manufacture of virus-based products.

Immunitrack provides a product and service pipeline to optimize immunogenicity assessments during drug development, as well as a broad portfolio of reagents to monitor patient CD8 and CD4 T cell responses to lead drug candidates during early R&D and clinical trials.

How Can Immunitrack Help R&D?
The Major Histocompatibility Complex (MHC) is critical to the immune response. Immunitrack has world-leading expertise in the manufacture and application of MHC I and II molecules to accurately study MHC epitope binding through our proprietary NeoScreen® platform.

Major Areas of Application
• Immuno-oncology: selection and study of neo-epitopes for personalized cancer vaccine development
• Vaccine development: selection of immunogenic epitopes from viral and bacterial targets
• Reducing immunogenicity of biologics: reduce the risk of anti-drug antibody development by identifying and removing CD4 T cell epitopes in candidate biologics.

Reagents
We produce customized MHC tetramers to detect and quantify subsets of patient immune (T) cells with specificity towards a given antigen within blood samples.

All of our MHC I reagents are produced on our optimized manufacturing platform, and we guarantee 100% peptide loading of each complex.

Binding Assays
Our unique NeoScreen® platform combines more than a decade of world-leading expertise in MHC/epitope binding assays with a high level of automation. The result is a highly scalable and accurate platform that can screen thousands of (neo-)epitopes.

Depending on the desired immune response our clients can then select and progress the best candidates through therapeutic development. Our repository is continuously growing, and currently holds more than 70 different MHC I and 20 MHC II alleles.

Interchim is a french company specialized in manufacturing and distribution of reagents, consumables and dedicated instruments for the R&D and QC laboratories in fields of
* Chromatography * Fine Chemistry * BioSciences *

Interchim aims to provide great solutions to researchers in biotechs, pharma, cosmetics, environement,... through a comprehensive range of innovative and convenient products and services - selecting best manufacturers and producing its own high quality products - , guaranteeing also excellent custom service.

Specialties in Chromatography:
HPLC, LC/MS, FPLC, MPLC - GC, GC/MS
GPC, GFC - RMN - AA, IR, ICP, UV - SPE
proprietary products: UptiSphere, Strategy, Atoll

Specialties in Fine Chemistry:
Chirals, Fluorinated, Building blocks for Combi-Chem
> 1 million of compounds

Specialties in BioSciences:
. Immunodetection: I and II antibodies and other immunologicals fo ELISA, WB, FCM, IH/IF, µarray...(i.e. substrates i.e. UptiLight ECL & TMB soln, kits,...)
. Proteomics: protein assays (BC Assay), Electrophoresis, MS, Crystalisation,...
. Cell Assays: viability (i.e.UptiBlue), apoptosis, calcium, signaling, adhesion, reporters,...

ReadyCell is a biotechnological company focused on providing sophisticated, cell based in vitro tools and R&D services for the ADME-Tox and Cosmetic segment. Our expertise include the manufacturing of patented, innovative cell-based and ready-to-use kits for efficacy and safety testing of active molecules as an alternative to animal testing, on drug discovery.

ReadyCell developed a patented technology that allows the shipment of living plated cells at room temperature. Maintaining their full viability and cellular characteristics, and thus allowing to streamline drug discovery pipelines and reducing experimental costs.

ReadyCell current Services portfolio covers a wide spectrum of drug discovery applications for in vitro and in silico screening, including adsorption, metabolism and toxicity assays.