BÜHLMANN Laboratories AG

Quality Assistance S.A. is a leading European Contract Research Organisation providing the pharmaceutical industry with all the analytical services required by EMA and FDA regulations for the development and marketing of innovative human medicinal products.

We assist our clients from candidate selection, through non-clinical and clinical studies, to marketing authorisation, using our state-of-the-art, product-dedicated expertise in analytical sciences.

For each customer and each project, we design customised solutions, define analytical protocols, develop and validate specific new analytical methods and perform characterisation, stability, pharmacokinetic, biomarker and immunogenicity studies as well as batch release testing, in order to evaluate the Quality, Safety and Efficacy of the given drugs.

Quality Assistance S.A. is an expert for the development of:
- Biologics (monoclonal antibodies, ADCs, proteins)
- New Chemical Entities, oligonucleotides, peptides
- Nanomedicine products
- Vaccines
- Cell-Based and Gene Therapy Medicinal Products

The company holds a unique position on the market with:
All its laboratories on one site (Donstiennes, Belgium)
- Bioanalysis (PK/TK/Immuno)
- Bioassays
- Biochemistry
- Chromatography
- Elemental Impurities
- Mass Spectrometry
- Microbiology
- Molecular Biology
- Protein Characterisation
200 highly qualified professionals
more than 35 years’ expertise at the forefront of analytical sciences.

Our core competencies are:
QUALITY (CMC)
- Development and validation of analytical methods
- Characterisation
- Stability studies
- Batch (release) testing
SAFETY/EFFICACY (Bioanalysis)
- Development and validation of bioanalytical methods
- PK/TK studies
- Immunogenicity studies
- Biomarker studies

The Quality Assistance environment is GMP, GLP and GCLP/GCP compliant.

Visit www.quality-assistance.com for more information

GEM FORLAB gives continuity to the experience of ABLE Biosciences as a global provider of scientific technology and services to the Life Science industry. It delivers solutions to companies of all size and shapes.
GEM FORLAB performs its activities by means of three technology areas:
Organic Chemistry
Mass Spectrometry & Proteomics
Cell and Molecular Biology & Immunoassay

ABLE Biosciences is the Test Facility GLP certified for small and large molecules quantitative analysis in biological matrices by means of Mass Spectrometry, Immunometric assays and qPCR and it is included in OsSC register of Private Laboratories qualified to perform analysis on samples derived from drug clinical trials (phase I-II-III) in compliance with GCP.

The Chemistry Unit provides all essential components for early drug discovery such as synthesis of chemical intermediates, process impurities, reference compounds, drug metabolites, and pro-drug; lead generation and optimization; bioconjugate chemistry; targeted molecules for MRI and others Molecular Imaging techniques.

Cruinn Diagnostics Ltd. was established in 1998 and has grown to become one of Ireland's leading suppliers in the Laboratory, Medical and Healthcare markets in Ireland.Our product portfolio covers a wide range of Diagnostics including Clinical Chemistry, Immunoassay, Haematology, Microbiology, AutoImmune Serology and recently the introduction of Real Time Molecular Diagnostics.

Other product portfolio's include Blood Collection Systems, POC, Laboratory Automation, Liquid handling Consumables, Healthcare IT Systems and Laboratory consumables.

Cruinn Diagnostics Ltd. now offers an accredited calibration and testing service in the areas of Temperature Controlled Enclosures, Controlled Environments e.g.Biological SafetyCabinets and Pipette Calibration

Fluofarma, a Porsolt company, joins drug discovery projects to bring tailored solutions in cell biology and high-content analysis. Specialized in assay design, the French preclinical CRO develops and performs cell-based assays and quantifies biomarkers in blood and tissues using different high-content imaging and flow cytometry technologies.

Fluofarma's contract research services are based on the following capacities:

CUSTOM BIOLOGICAL MODELS

> Generation of primary cell cultures, cell lines, 3D spheroids
> Development of multi-cell type culture systems in 2D & 3D
> Preclinical and clinical samples : whole blood, solid tissues and tissue microarrays (TMAs)

ADAPTATION & DEVELOPMENT OF CELL-BASED ASSAYS

> 100 phenotypic and molecular assays for immediate performance or adaptation to specific cell types
> Multiplexing, miniaturization, automation of cell-based assays
> Assay development with the cellular model, readout, and high-content screening technology needed

BIOMARKER ANALYSIS

> Design and development of biomarker assays
> Automated biomarker quantification in tissue sections and tissue microarrays (TMAs)
> Biomarker analysis in whole blood by high-throughput flow cytometry

Since 2003, Fluofarma has been supporting over 70 pharmaceutical companies in the dicovery of new therapeutic targets, compounds and biomarkers.

To learn more about Fluofarma’s contract research services, please visit www.fluofarma.com

💡 A biotechnology group based on complementary expertise with multidisciplinary know-how

Custom Products & Services delivering a range of integrated biotechnology solutions 🤝

🏢 COMPANIES:

- RD-Biotech SAS (www.rd-biotech.com):
Custom services, Biomanufacturing and purification (monoclonal antibodies, recombinant proteins, plasmids, cells), hybridoma development, expression vectors, transfection, antibody sequencing, chimerization and humanization, analytical services and FastELISA kits for Immunoglobulins quantification and cellular contaminants detection.

- SYnAbs (www.synabs.be):
Primary and Secondary Antibodies Anti-species, Isotype controls, custom services, hybridoma development – rat, guinea pig, murine, Immunoassays

- QVQ (www.qvquality.com)
VHH Phage display services and a large range of VHH products

- Smaltis (www.smaltis.fr)
CRO specialized in microbiology, an high expertise in the fileds of antibiotic resistance, microbiota and strain engineering. Custom services and a large collection of genetically modified bacterial strains.

📈 EFFECTIVE SYNERGY

As part of a team of experts to ensure:
- The development of new biological tools in immunology, molecular biology, cellular engineering
- Identification of new markers
- The development of analytical methods
- Scientific and technical support
- The quality of services and products developed and manufactured in-house

✔ MAIN SECTORS OF ACTIVITY

- Pharmaceutical
- BioTherapeutics
- Biotechnology
- In vitro diagnostics
- Animal health
- Dermo-cosmetic
- Agribusiness
- Life sciences
- Environment
- Research Institutes