BMA Biomedicals

Accelerō® Bioanalytics GmbH is a certified GLP test facility, and operates in compliance with ICH GCP regulations. Competent authorities approved Accelero´s Biosafety Level S2 laboratories for both microbiology and genetic engineering.

Accelero is proud to serve our clients with:

• OECD GLP approved facilities for analytical, non-clinical studies.
• ICH E6 R1 GCP compliant analytical facility for clinical phase 0 to 3 studies.
• Facility approved for handling and cultivation of BSL-2 micro-organisms (bacteria, yeasts).
• Facility approved for genetic engineering / cloning / analysis of safety level S2 GMOs
(bacteria, yeasts, viruses, plants, animals).
• Approval for the import and analysis of animal by-products from non-EU countries (e.g. like U.S.A., China).

Accelero services include, but are not limited to:

• Pharmacokinetic / toxicokinetic characterization (ELISA, qPCR, immuno qPCR).
• Biodistribution and shedding (qPCR).
• Biomarker screening on the RNA level (qPCR, microarray) and the protein level (microarray).
• Cell-based in vitro immunoassays (ELISA, EliSpot, flow cytometry).
• Particle-based multiplex immunoassays (flow cytometry).
• Particle-based multiplex miRNA (microRNA) assays (flow cytometry).
• Cell proliferation and cytotoxicity assays (flow cytometry, EliSpot).
• Gene expression assays (RTqPCR).
• GLP training services (basic courses, in-house trainings).
• Antibody detection assays (ADA): screening, confirmatory, neutralization (EliSPOT).
• Preclinical consulting services with regards to GLP and bioanalysis.
• Complement activation monitoring.
• Supply chain services e.g. like sample transport and shipping organisation, preparation of clinical kits.

All analytical methods are developed and validated according to the respective EMA, FDA, and/or ICH guidelines.

Accelero® is a trademark fully owned by Accelero Bioanalytics GmbH, Berlin (Germany).

Last update of this page: 31-DEC-2017 by CL

AcZon is an Italian Company specializing in biotechnology that develops, produces and commercializes Silica Nanoparticles (Nanoprobes) - for diagnostic, clinical and research fields- as well as a range of conventional reagents optimized for various applications as, for example, fluorescent antibodies. People’s Health is the main focus and ultimate goal of our business; our “mission” is basically “To promote and providing Reagents for Diagnostics and Research, with very high brilliance and clarity of image, stability and sensitivity, by offering products and services that speed-up the diagnostic response time, provide a better service to the patient”. AcZon focuses with growing interest on the amazing potentials offered by combining chemistry, biotechnology and nanotechnology. Indeed, on this basis, AcZon has developed and optimized a line of new products (reagents for in vitro diagnostics and research) characterized by outstanding performances. Thanks to its team of researchers (chemists and biologists), all with considerable experience in the synthesis and functionalization of polymers and in the fields of immunology, proteins and bio-conjugations, AcZon has developed, and is now producing, a line of NanoProbes (proprietary technology), based on Silica NanoParticles (NPs), which are not exclusively suitable for diagnostic and clinical applications, but also for chemistry, pharmacy, agriculture and the environment

Pioneer in antibodies’ field, Agro-Bio provides you its expertise and its know-how for production, development and characterization of antibodies. For over 40 years, our team supports pharmaceutical and in vitro diagnostic industries as well as public institutions for their immunology issues. We collaborate both to offer you the most suitable and effective solution. Our goal is the success of your projects.

Our services around antibody:
• Bioanalysis/Biopharma:
o Anti-idiotypic antibodies for positive control, PK and potency test,
o Host Cell Protein issue management: specific anti-HCP antibodies, 2D Western Blot coverage analysis, specific ELISA kit,
o Epitope mapping,
o In vitro production.
• In vitro diagnostic:
o Bulk antibody production,
o Specific polyclonal and monoclonal antibody development,
o Characterization of antibodies: Biacore T200…

Our key strengths to ensure a quality work:
• Over 40 years’ experience in antibody area,
• Responsive, multi-skilled and comprehensive team,
• Certifications ISO 90001:2015 and ISO 13485:2016,
• Research Taxe Credit approval,
• Preserved intellectual propriety and confidentiality,
• Transparency for monitoring and management of your project,
• Royalty-free services.

Premiere European CMO with production facilities for murine monoclonal antibodies for use in biopharmaceuticals, human diagnostics, veterinary diagnostics & food analysis.

Diatec Monoclonals is an experienced and flexible partner for your antibody production outsourcing needs. Diatec Monoclonals offers a complete range of services from establishment of hybridomas and cell banking, in vitro antibody production and downstream processing of the product.

Diatec Monoclonals offers excellence in service standards, technical support and product quality supported by a competitive pricing strategy.

Your preferred partner for ISO and cGMP production.

Explicyte is a family brand of specialty preclinical services launched by ImmuSmol, a bordeaux-based company. The first brand, Explicyte Immune-Oncology offers preclinical contract research services in immuno-oncology.

Explicyte Immuno-Oncology currently offers to test innovative cancer immunotherapies in vivo, using syngeneic mouse tumor models treated with immune checkpoint inhibitors (eg. anti-CTLA-4 and anti-PD1/PD-L1 antibodies). In addition, Explicyte is setting up an in vitro platform for the identification and optimization of novel immunomodulators. Equipped with high-content analysis technologies, the platform focuses on live phenotypic screening in co-cultures of immune and cancer cells, as well as molecular cell-based assays for the assessment of immune checkpoint inhibitors.