Base Pair Biotechnologies, Inc.

AM Biotechnologies, LLC is dedicated to the development and commercialization of aptamer technology and its products. Specifically, we develop synthetic affinity reagents called X-Aptamers for applications in life science research, diagnostics and therapeutics. X-Aptamers provide the performance of monoclonal antibodies but avoid many of the problems associated with them.

An X-Aptamer is an affinity agent (similar in function to an antibody) that is comprised of a single strand of DNA with one or more (usually several) non-DNA chemical modifications attached to one or more of the DNA bases. An X-Aptamer has much greater chemical diversity than an aptamer. X-Aptamers use combinations of chemically-modified DNA bases and backbones that typically cannot be amplified using PCR. This makes it impossible to select X-Aptamers using the typical enzymatic processes used to select aptamers (e.g. SELEX). The diversity of the chemical functional groups in X-Aptamers provides much better interaction with a target, which typically results in better binding affinity and specificity.

Aviva Systems Biology specializes in providing polyclonal and monoclonal antibodies, ELISA kits, proteins, and custom services for research needs. We manufacture 24,000 validated polyclonal antibodies and offer nearly 20,000 ELISA kits. Our custom laboratory services include protein expression and purification, antibody development, and ELISA development, validation, and production.

Our head office is in San Diego, CA, we also have an office in Beijing, China. Both locations provide scientific support assisting researchers with a variety of proteomic objectives.

Aviva provides unique tools for research associated to unique species and targets. The company's products are relevant to 10,000 unique species, 10,000 cellular processes, and 5,000 protein pathways.

Research Areas
Transcription factors, cancer, cardiovascular, cell biology, DNA damage and repair, epigenetics, signal transduction, cell differentiation, stem cell biology , and many more.

Specialties
Western blot, immunohistochemistry, ELISA, custom protein expression

Bangs Labs'​ 30 years of experience in microsphere & nanoparticle synthesis and fine particle analysis have established us as a leading manufacturer of polymer, silica & magnetic microspheres to laboratory instrument manufacturers and diagnostic assay developers. Our dyeing, coating & surface modification capabilities are demonstrated in our specialty products for bioseparations (DNA, antibodies, cells,..) and instrument standardization (flow cytometry, cell counters / viability analyzers, microscopes,..). Give us a call and let us put our decades of real-world experience to work for you!
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As a Contract Development and Manufacturing Organization (CDMO), the Boston Institute of Biotechnology, LLC, provides full-spectrum services for microbial fermentation and mammalian cell culture processes.

Boston BIB occupies a facility of 6,000 sf. that includes isolated laboratory spaces for cell culture, fermentation, purification and analytical services.

Our facility in Southborough MA, within the Genetown Hotbed of Metro-Boston Area, offers flexible and adaptable lab spaces designed to meet the needs of our clients
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Our mission is to be a trustable partner to our clients by delivering robust bioprocess solutions on time.

BIB is dedicated to building up long-term strategic partnerships with the clients. We value the success of our clients as our success, and stand by our clients along with his way to the success.

From DNA to clone selection and stability, BIB can provide strain and cell line development work based on the extensive industry experience with different types of mammalian cell lines, as well as several kinds of micro-organisms.

Boston Institute of Biotechnology develops and runs reproducible, robust and scalable microbial fermentation and mammalian cell culture process for the production of therapeutic protein and antibodies.

We have years of experience with fermentation and mammalian cell culture technologies to meet the future commercial requirement such as high throughput process development technologies, disposable mini bioreactors, high cell density screening, and complex system optimization.

Founded in 2002, CELPROGEN is a biotechnology company, with over 5000 products in the market, focused on developing stem cell research and therapeutics products for regenerative medicine in cardiology, oncology, diabetes & neurology. All of Celprogen’s biological products, including stem cells, cancer stem cells, iPC’s & media with specific ECM’s, are manufactured and produced in the United States of America.

CELPROGEN provides novel molecular diagnostics and therapeutic product development solutions for Biotechnology, Pharmaceutical, In-vitro diagnostics and academic partnership for drug discovery.

It has 3 divisions:

• Therapeutic Division: Focused on Drug Discovery efforts to develop Pharmaceutical agents and Drugs in the following categories: Cardiovascular, Diabetes, Neurological, Oncology,Renal and Metabolic disorders.
• Life Science Division: Provides research tools & solutions for assays, enzymes, antibodies, antigens, stem cells, Tissue culture expansion and differentiation media, primary and established cell cultures, tumor markers, cardiac markers, proteomic and genomic reagents and assay systems for life science academic and pharmaceutical communities.
• Device Division: Provides novel ELISA based assay, protein array, DNA array and cellular based assay systems that are cost effective for Research and In-vitro diagnostics Industries.