Astrea Bioseparations Ltd

Biopolis, S.L. is a leading microbial biotechnology company based in Valencia (Spain) offering Contract Research and Manufacturing. Our core competences are the isolation, selection, design, characterization, validation and production of microorganisms and cellular metabolites with applications in agrifood, feed, pharmaceutical, chemical and environment industries.

As Tailor-made Biotechnological company, we develop solutions for our clients even if Biopolis has internal R&D research lines.

Prototype projects (i) the selection, validation and production of functional probiotics and starters, (ii) the identification, characterization and process development of functional ingredients, (iii) the overexpression of recombinant protein in microbial systems, (iv) the overproduction of synthesis intermediates and active pharmaceutical ingredients (v) the design of novel processes based on microbial and enzymatic catalysis for bulk chemical production (vi) the selection and production of enzymes and (vii) the revaluation of waste and by-products of industry.

Biopolis facilities spread over 1500 m2, hosting 9 specialized research laboratories distributed in 3 Departments (Agri-food Biotechnology, Microbian Biotechnology and Production capacity of 9000 L fermentation).
We offer omics technologies (transcriptomics, metabolomics, and metagenomics) to guarantee a complete service to our customers.

BLIRT (Biolab Innovative Research Technologies) is a modern European biotech manufacturer of high quality specialty enzymes and reagents dedicated for application in Life Science.

For over 25 years, BLIRT has been specializing in providing the highest quality products for researchers and scientists. Since 1994, the company began operating in the Polish market as DNA-Gdańsk. From 2007, the company developed and further expanded brand as BLIRT.
A brand new manufacturing facility, commissioned in the late fall of 2017, allows BLIRT to deliver kilogram quantities of any protein expressed in yeast, or bacteria. Every protein in BLIRT’s portfolio is free of any third party IP.

BLIRT also manufactures and sells convenient kits for DNA/RNA isolation and Real-Time PCR. All critical enzymes for the kits are produced internally. Those kits provide excellent yields and added convenience comparing to other products available on the market.

BLIRT’s experience and expertise in development of protein production methods (upstream and downstream), combined with its commercial protein production capacity, makes it an ideal choice for a full service CMO.

BLIRT has three sites in Poland: R&D site, Kits manufacturing facility, and protein production facility.

Every day hundreds of thousands of people around the world are in touch with a food, pharma, personal care or industrial product that has been handled with care by Caldic. At Caldic we are the linking pin, connecting people, products and solutions for a better world. But we go beyond connecting to ensure we deliver on our business partners’ requirements for added-value R&D, manufacturing and packaging solutions, while minimizing the environmental impact. This makes Caldic the partner of choice in innovative and sustainable solutions in life science and specialty chemicals.

Our tagline ‘Because we care’ underlines our commitment to our people, our business partners and our planet. On a daily basis around 1200 Caldic employees go the extra mile to deliver value-add solutions. Caldic is present in 19 countries in Europe, North America and Asia Pacific.

For more information, please visit www.caldic.com.

Awarded as Most Innovative Company in 2014, with 10 Technologies Patented Worldwide or Unprecedented Milestones achieved, Canvax™ manafactures High Quality & Low Price products inside next categories: DNA Cloning, Mammalian & Bacterial Expression, Dual Reporters, GPCRs, Cell Lines, Viral Packing Systems, DNA & RNA Extraction kits, Cell Assays, PCR & qPCR Essentials, Food Science, Recombinant Proteins, Custom Solutions, R&D Services, and much more Innovative Solutions.

Currently, we are one of the fastest growing Life Science Companies thanks the commitment of our 26 employees with the Culture of Excellence through our advanced Manufacturing and Quality-control systems, in-depth market knowledge, best delivery rates, World-class technical Distributor Support, training, Breakthrough Promotions and R&D capabilities.

Cerbios is a swiss privately held company specialized in the development and manufacturing of chemical and biological APIs for its world-wide partners.

The exclusive R&D and manufacturing expertise is available to our Pharma partners needing to develop and scale-up NCE or NBE for clinical trials, registration and commercial purpose.

cGMP APIs made by Cerbios in its FDA inspected site in Switzerland are sold worldwide mainly to pharma companies including EU, USA and Japan.

Cerbios is specialized in Reduced Folates (world leader position) but also in the manufacturing of High Potency Active Ingredients (HPAPIs) with a series of Vitamin D derivatives requiring sophisticated production units with high containment levels.

Another core business is the research, development and production of Probiotics of Pharma quality.
On top of that, in the last 17 years, CERBIOS has acquired a vast experience with Recombinant Proteins from mammalian cells (CHO) based on a state-of-the-art platform.

Service for third parties in exclusive manufacturing is concentrated in the area of HPAPI and Recombinant Proteins.

Full CMC support is given to our customers in order to provide them with the supply of cGMP clinical batches, registration/validation material and commercial manufacturing. Paramount to that is the supply of all documentation required for a successful registration.