Addgene

EpigenDx was incorporated in 2006 as a genomic and epigenomic research company specializing in disease biomarker discovery, validation and molecular diagnosis, with an unmatched expertise in the field of DNA methylation analysis.

EpigenDx provides superior products and laboratory services for scientific researchers from academic, government and industrial communities from all over the world. Our commitment to quality reflects our desire and dedication to provide the best products and services to our customers. EpigenDx has extensive knowledge and expertise in Pyrosequencing, bisulfite sequencing, and various epigenomic research analysis techniques and methods stemming from our years of experience in the industry.

EpigenDx Lab Services include:
DNA Methylation
- Bisulfite Pyrosequencing: determine loci specific methylation and global methylation levels individual CpGs sites
- Targeted MethylSeq: determine methylation levels in multiple targeted regions at base pair resolution
Expression Analysis
- Gene and miRNA profiling using Affymetrix Gene Chip arrays
Mutation & SNP Analysis
- Quantative mutation analysis using Pyrosequencing for minor allele detection, allele specific expression
- 1.8 million SNPs and copy number changes using Affymetrix 6.0 Array

EpigenDx products include:
DNA Methylation Controls: low and high methylated genomic DNA for studying human, mouse, rat genes
Validated loci specific DNA methylation assays for multiple platforms including bisulfite sequencing, bisulfite Pyrosequencing, and realtime based PCR analysis. All assays are validated for PCR bias or preferential amplification.
Methylation Panels including Stem Cell Panel, Cancer Panel, Immunology Panel, and CNS Panel. They are designed for bisulfite sequencing analysis using either Pyrosequencing or NGS platforms.

Founded in 1997, Alkemist Labs is a pioneer in botanical identity testing with expanded capabilities in phytochemical potency analysis. We are passionate about full method transparency, personalized technical support, and unrivaled customer service. With our expertise in this very specialized testing niche, we can help you in all aspects of ensuring that you know exactly what is in your products. Alkemist Labs helps companies achieve and maintain quality products and cGMP compliance.

In addition to services such as identity verification by HPTLC and microscopy and potency testing by HPLC and GC, we now offer Next-Generation DNA Sequencing as a new powerful tool available for speciation in plant-based products. Because this technology has often been misapplied and standard methods are not yet developed, Alkemist Labs uses this platform alongside more established and accepted testing methods in order to accelerate understanding of this technology and help make it one of the useful testing tools for dietary supplements and ingredients.

Alkemist Lab’s mission is to bring transparency to all areas of natural products industry testing includes education tools designed to demystify testing and help companies obtain accurate results to support regulatory compliance and illustrate their quality commitment to consumers.

In addition to our testing services, Alkemist also offers a full catalog of reference materials to be used by your in-house laboratory. These critical tools for botanical identity verification, including the Alkemist Labs complete line of Composite Reference Botanicals (CRBs), AHP-Verified Botanical Reference Materials (BRMs), all easily purchased through the Alkemist e-commerce section of the website.

We are hiring! We are looking for talented Scientists, Chemists, Analysts, Technicians and Quality Assurance personnel. For more information, visit www.alkemist.com/job-openings/

Alta Biotech is a fast-growing global contract research organization specializing in molecular biology, biochemistry and cell biology services. Our core area of expertise includes plasmid DNA purification, gDNA and total RNA extraction, gene synthesis and a wide portfolio of customized fundamental life science research support services. With facilities located in the heart of the Fitzsimons Life Science District in Colorado, Alta Biotech has developed a variety of in-house technology platforms to provide fast, high-quality, and cost-effective services to exceed customer expectations. Our goal is to serve as a trusted bioscience partner to our customers.

Bio-synthesis is a biology contract manufacturer of high quality nucleic acids, peptides and other molecular biology products for the research, diagnostic and therapeutic industries. Bio-Synthesis operates an ISO 9001 certified facility and is compliant with 21 CFR 210/211 and 21 CFR 820. Our solutions help advance drug discovery and bio-medical research. Founded in 1984, Bio-Synthesis is a privately held firm based in Lewisville, Texas.

Custom Peptide Specialists
Bio-Synthesis has been a provider of Peptide Synthesis services to the life science research community since 1984. We offer a complete range of premium quality peptide products ranging from bulk API polypeptides to high throughput library peptides and peptide array preparation. We also provide a large number of peptide modifications as well as peptide synthesis for diagnostic and therapeutic applications. Bio-Synthesis specializes in both, liquid phase and solid phase fmoc peptide synthesis chemistry. We have a long standing record in preparing biologically active polypeptides including long, complex and hydrophobic peptides synthesized to your specifications.

Custom Oligonucleotide Specialists
As a pioneer in oligonucleotide synthesis, Bio-Synthesis has been pursuing the development of new oligonucleotide-based techniques that can produce compounds with superior binding affinity and chemical/biological stability. As such, Bio-Synthesis has introduced a third generation of nucleic acid analogs, Bridged Nucleic Acid (BNA). These are RNA analogues which can be synthesized and spiked with DNA or RNA in order to modify the formation of nucleic acid helices.

Biotheranostics, Inc., is a leader in helping physicians improve the care of cancer patients, offering a suite of proprietary genomics-based molecular diagnostics that allow treatment to be tailored to individual patients.

The company’s CancerTYPE ID® is the most rigorously validated gene expression test for metastatic patients with diagnostic ambiguity, helping physicians determine optimal site-directed treatment regimens with the goal of improving patient outcomes.

Its Breast Cancer IndexSM helps oncologists make difficult decisions about extended endocrine therapy for ER+ breast cancer patients based on its unique ability to predict risk of late disease recurrence and identify which patients are likely to benefit from continuing therapy beyond five years.

Biotheranostics operates a CLIA-certified, CAP-accredited diagnostic laboratory in San Diego. Learn more at biotheranostics.com.